Shelf life of predosed plates containing mefloquine, artemisinin, dihydroartemisinin, and artesunate as used for in vitro Plasmodium falciparum susceptibility assessment |
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| Authors: | Houzé Sandrine Munier Aline Paoletti Xavier Kaddouri Halima Ringwald Pascal Le Bras Jacques |
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| Affiliation: | Laboratoire de Parasitologie, Centre National de Référence du Paludisme, Assistance Publique-H?pitaux de Paris, H?pital Bichat-Claude Bernard, and Université Paris Descartes, EA 209, Paris, France. sandrine.houze@bch.aphp.fr |
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| Abstract: | ![]()
The shelf lives of preserved antimalarial agent-predosed plates according to the type of wrapping and the temperature of storage were studied by measuring the 50% inhibitory concentrations of drug for Plasmodium falciparum 3D7. The shelf life of mefloquine was 8 weeks at 25 degrees C; and those of artesunate, artemisinin, and dihydroartemisinin were a minimum of 24, 12, and 8 weeks, respectively, at 4 degrees C. |
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