DTI在涉及皮质脊髓束缺血性脑梗塞中的应用

目的:探讨磁共振弥散张量成像(DTI)在涉及皮质脊髓束的缺血性脑梗塞的应用价值。方法:应用西门子1.5TMR成像系统,对30例累及内囊后肢或放射冠的脑梗塞患者进行检查,均行DTI序列(b值=0,500s/mm2)及颅脑MRI扫描,在Siemens Leonardo工作站应用纤维束跟踪软件(Siemens Standar 12 dirs)进行后处理。结果:梗塞灶FA值较对侧相应部位明显降低,ADC值较对侧相应部位明显升高,皮质脊髓束穿过梗塞灶的患者运动功能恢复较差,皮质脊髓束未穿过梗塞灶的患者运动功能恢复较好。结论:DTI白质纤维束成像可以无创性显示皮质脊髓束与缺血性梗塞灶的空间关系,帮助判断运动功能受损情况与预测预后。

Application of diffusion tensor imaging in ischaemic stroke affecting the motor system

Objective:Using diffusion tensor imaging to show corticospinal tract in patients with ischaemic stroke.Methods:30 patients with ischaemic stroke involved the posterior limb of the internal capsule or corona radiata were studied with DTI(b value=0,500s/mm2) and routine MRI.Post processing was made on Siemens leonardo workstation.Results:FA values of infarct areas were declined and ADCs were raised.The patients with corticospinal tract runing through the infarct made a poor recovery,those not runing through the infarct made an excellent recovery.Conclusion:3D tractography can noninvasively show the spatial relationship of corticospinal tract and infarct areas.It is useful in evaluating the recovery of motor function.