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| 石菖蒲乙醇提取物的化学成分及体外抗疲劳活性研究 | |
| 引用本文： | 朱梅菊,谭宁华,熊静宇,嵇长久,朱红竹,徐俊驹,罗齐军. 石菖蒲乙醇提取物的化学成分及体外抗疲劳活性研究[J]. 中国中药杂志, 2012, 37(19): 2898-2901 |
| 作者姓名： | 朱梅菊 谭宁华 熊静宇 嵇长久 朱红竹 徐俊驹 罗齐军 |
| 作者单位： | 1. 湛江师范学院 体育科学学院,广东 湛江 524048;井冈山大学 体育学院,江西 吉安 343009 2. 中国科学院 昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室,云南 昆明,650204 3. 湛江师范学院 体育科学学院,广东 湛江,524048 4. 井冈山大学 体育学院,江西 吉安,343009 |
| 基金项目： | 国家自然科学基金项目(31160217,30725048);广东省自然科学基金项目(31938,10152404801000008) |
| 摘 要： | 采用柱色谱等分离手段,研究石菖蒲乙醇提取物中乙酸乙酯和正丁醇萃取部分的化学成分;并运用体外抗蟾蜍骨骼肌疲劳模型对分离得到的化合物进行抗疲劳活性研究.结果分离得到5个化合物,经波谱分析鉴定为细辛酮(1),环木菠萝烯酮(2),2,4,5-三甲氧基-2′-丁氧基-1,2-苯丙二醇(3),5-羟甲基糠醛(4),5-丁氧甲基糠醛(5).化合物3是新化合物,化合物2和5是首次从该植物中分离得到.化合物4具有明显的体外抗骨骼肌疲劳活性. |
| 关 键 词： | 石菖蒲 化学成分 抗疲劳 |
| 收稿时间： | 2011-12-01 |
Chemical constituents contained in ethanol extracts from Acorus tatarinowii and their anti-fatigue activity |
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| ZHU Mei-ju,TAN Ning-hu,XIONG Jing-yu,JI Chang-jiu,ZHU Hong-zhu,XU Jun-ju and LUO Qi-jun. Chemical constituents contained in ethanol extracts from Acorus tatarinowii and their anti-fatigue activity[J]. China Journal of Chinese Materia Medica, 2012, 37(19): 2898-2901 | |
| Authors: | ZHU Mei-ju TAN Ning-hu XIONG Jing-yu JI Chang-jiu ZHU Hong-zhu XU Jun-ju LUO Qi-jun |
| Affiliation: | Institute of Sports Science, Zhanjiang Normal College, Zhanjiang 524048, China;School of Sports Science, Jinggangshan University, Ji'an 343009, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;Institute of Sports Science, Zhanjiang Normal College, Zhanjiang 524048, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;School of Sports Science, Jinggangshan University, Ji'an 343009, China;State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;Institute of Sports Science, Zhanjiang Normal College, Zhanjiang 524048, China |
| Abstract: | Chemical constituents in ethyl acetate and butanol fractions of ethanol extracts from Acorus tatarinowii were separated by column chromatography. Bufo skeletal muscle fatigue model was established to study the anti-fatigue activity of separated compounds. Five compounds were separated and identified by spectroscopic analysis as acoramone(1),cycloartenone(2),2,4,5-trimethoxyl-2'-butoxy-1,2-phenyl propandiol(3),5-hydroxymethyl furfural(4),and 5-butoxymethyl furfural(5). Compound 3 was a new compound,and compounds 2 and 5 were separated from this plant for the first time. Compound 4 exhibited a notable anti-fatigue activity. |
| Keywords: | Acorus tatarinowii chemical constituent anti-fatigue activity |
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