弹簧圈介入栓塞治疗脑动脉瘤的临床效果观察

目的探讨弹簧圈介入栓塞治疗脑动脉瘤的效果，评价其临床应用价值。方法随机选取2008年5月～2012年5月至本院住院治疗的脑动脉瘤患者285例，将其分为两组，观察组行弹簧圈介入栓塞治疗，对照组行显微手术夹闭，观察并比较两组的死亡率及再出血、脑血管痉挛、脑积水等并发症发生率．比较两组手术期间出血量及术后恢复时间，随访半年后分析两组的MBI评分等。结果两组患者均得到良好恢复，两组的再出血、脑血管痉挛、脑积水发生率及死亡率比较，差异无统计学意义（P〉0．05）；两组的MBI评分比较差异无统计学意义（P〉0．05）；观察组手术期间出血量少于对照组，术后恢复时间短于对照组，差异有统计学意义（P〈0．05）。结论弹簧圈介入栓塞治疗脑动脉瘤与显微手术治疗效果相当，但具有操作简单、创伤小、恢复快的优势，值得临床推广应用。

Clinical effect observation of coil embolization in the treatment of cerebral aneurysm

Objective To discuss the effect of coil embolization in the treatment of cerebral aneurysm and evaluate its clinical application value. Methods 285 cases of patients with cerebral aneurysms from May 2008 to May 2012 in our hospital were selected and randomly divided into two groups.Coil embolization was given in observation group and microsurgery occlusion was given in control group.After treatment,mortality rate and rate of re-bleeding,cerebral vasospasm,and hydrocephalus was observed and compared respectively between two groups.The perioperative blood loss and postoperative recovery time was compared respectively in two groups.MBI score of two groups was analyzed after a follow-up of six months. Results All patients in both groups got good recovery.There were no statistical difference in mortality rate,rate of releeding,cerebral vasospasm and hydrocephalus between two groups（P〉0.05）.MBI score between two groups was compared,with no statistical difference （P〉0.05）.Intraoperative blood loss in observation group was less than that in control group,postoperative recovery time in observation group was shorter than that in control group,with statistical difference （P〈0.05）. Conclusion Coil embolization of cerebral aneurysm and microsurgical treatment effect is quite,but has advantages of simple operation,little trauma,quick recovery,thereby it is worthy of clinical promotion and application.