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| P27蛋白在牙源性肿瘤的表达 | |
| 引用本文： | 王炼,卢勇,魏于全,吴兰雁,杨橙,蔡益新. P27蛋白在牙源性肿瘤的表达[J]. 华西口腔医学杂志, 1998, 16(1): 0-11,T002 |
| 作者姓名： | 王炼 卢勇 魏于全 吴兰雁 杨橙 蔡益新 |
| 作者单位： | 华西医科大学口腔医学院口腔组织病理学教研室,华西医科大学第一临床医学院肿瘤生物治疗中心,华西医科大学口腔医学院重点实验室 |
| 摘 要： | 采用免疫组织化学Ｓ－Ｐ法检测４０例牙源性肿瘤中Ｐ２７蛋白表达情况。结果显示：不同类型牙源性肿瘤中有不同表达，良性肿瘤组表达率为３０．０％（６／２０），恶性肿瘤组为８５．０％（１７／２０），良恶性肿瘤组之间差异显著（Ｐ＜０．００５）。提示Ｐ２７蛋白可能成为牙源性肿瘤有一定辅助诊断价值的标记物 |
| 关 键 词： | P27蛋白 牙源性肿瘤 免疫组织化学 |
| 收稿时间： | 1998-02-25 |
| 修稿时间： | 1998-02-25 |
Expression of P27 Protein in Odontogenic Tumors |
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| L Wang,Y Lu,L Wu,Y Wei. Expression of P27 Protein in Odontogenic Tumors[J]. West China journal of stomatology, 1998, 16(1): 0-11,T002 | |
| Authors: | L Wang Y Lu L Wu Y Wei |
| Affiliation: | College of Stomatology, West China University of Medical Sciences. |
| Abstract: | The expression of P27 protein was investigated in 40 cases of odontogenic tumors by immunohistochemical S-P assay. The results showed that P27 expression varied in different types of odontogenic tumors. Positive signals were present in 17/20 (85.0%) of the malignant odontogenic tumors, but in 6/20 (30.3%) of the benign ones (P < 0.005). It was suggested that P27 protein had certain practical value in the differentiation diagnosis of odontogenic tumors. |
| Keywords: | P27 protein odontogenic tumor immunochemical technique |
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