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Adenovirus Coding for Interleukin-2 and Tumor Necrosis Factor Alpha Replaces Lymphodepleting Chemotherapy in Adoptive T Cell Therapy |
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| Authors: | João Manuel Santos Víctor Cervera-Carrascon Riikka Havunen Sadia Zafar Mikko Siurala Suvi Sorsa Marjukka Anttila Anna Kanerva Akseli Hemminki |
| Institution: | 1. TILT Biotherapeutics Ltd., 00290 Helsinki, Finland;2. Cancer Gene Therapy Group, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland;3. Pathology Unit, Finnish Food Safety Authority (EVIRA), 00790 Helsinki, Finland;4. Department of Obstetrics and Gynecology, Helsinki University Hospital, 00290 Helsinki, Finland;5. Helsinki University Hospital Comprehensive Cancer Center, 00290 Helsinki, Finland |
| Abstract: | |
| Keywords: | oncolytic adenovirus adoptive T cell therapy lymphodepleting preconditioning interleukin-2 tumor necrosis factor alpha chemotherapy TIL therapy TCR modified T cell therapy |
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