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Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer
Authors:Lina Liu  Yuhua Wang  Lei Miao  Qi Liu  Sara Musetti  Jun Li  Leaf Huang
Affiliation:1. Division of Pharmacoengineering and Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA;2. UNC and NCSU Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA;3. Key Laboratory of Biological and Medical Engineering and Engineering Research Center of Medical Biotechnology and Guizhou Provincial Engineering Research Center for Immune Cells and Antibody, School of Biology and Engineering, Guizhou Medical University, Guiyang, Guizhou 550025, PR China
Abstract:
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  • Keywords:mRNA nano-vaccine  CTLA-4 blockade  triple negative breast cancer
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