舒适护理对结肠癌术后化疗患者康复效果及癌因性疲乏的影响研究

目的:探讨舒适护理对结肠癌术后化疗患者癌因性疲乏的影响. 方法:选择符合标准的患者60例,随机分为观察组和对照组各30例,两组患者均给予常规护理,观察组此基础上实施舒适护理,采用欧洲癌症研究与治疗组织( EORTC)编制的生活质量核心问卷( QLQ-C30)中的5个功能量表进行康复效果,癌因性疲乏采用简明疲乏量表( BFI )进行评价. 结果:术前,两组患者QLQ-C30功能量表各维度评分相似,差异无统计学意义( P>0.05);两个疗程化疗结束时,两组患者QLQ—C30功能量表各维度评分较术前增加,但是观察组各项指标评分明显高于对照组,差异有统计学意义( P<0. 05). 术前,两组患者BFI评分相似,差异无统计学意义( P>0.05);化疗第14天和第28天,两组患者BFI评分较术前均增加,但是观察组患者增加幅度小于对照组,差异有统计学意义( P<0.05). 结论:舒适护理可明显改善结肠癌术后化疗患者癌因性疲乏程度,促进患者术后康复,提高生活质量.

The Effect of Comfortable Nursing on Cancer Related Fatigue and Rehabilitation Efficacy of Patients Under Chemotherapy after Surgery for Colon Cancer

Objective:To investigate the effect of comfortable nursing on cancer related fatigue and to promote the postoperative rehabilitation of patients under chemotherapies after surgeries for colon cancer. Method:A total of 60 eligible patients were selected and randomly divided into observation group and con-trol group, with 30 patients in each group. The patients of both groups were given usual care, while the ob-servation group given comfortable nursing additionally. The rehabilitation efficacy was evaluated by the five functional scales of quality of life questionnaire ( QLQ-C30 ) of European Organization for Research on the Treatment of Cancer ( EORTC) , and cancer related fatigue evaluated by Brief Fatigue Inventory ( BFI) . Re-sult:Before the surgery, the patients of the two groups had similar QLQ - C30 functional scale scores ( P>0.05);at the end of 2 courses of chemotherapy, the patients of both groups had increased QLQ -C30 func-tional scale scores compared with those before the surgeries, but the observation group had significantly high-er functional scale scores than those in the control group (all P<0.05). Before the surgery, the patients of the two groups had similar BFI scores ( P>0.05);at the 14th day and the 28th day after the chemotherapy, the patients of both groups had increased BFI scores compared with those before the surgeries, but the pa-tients of the observation group had a smaller increasing extent than the control group, and the difference was statistically significant ( P<0.05) . Conclusion: Comfortable nursing can significantly improve the degree of cancer related fatigue, promote the postoperative rehabilitation, and elevate the quality of life in patients un-der chemotherapy after surgery for colon cancer.