“养髓益智”组穴针刺治疗血管性认知障碍(肾精亏虚型)的临床观察

目的:观察"养髓益智"组穴针刺治疗血管性认知障碍(肾精亏虚型)的临床疗效。方法:将60例符合条件的患者,按随机数字表法随机分为对照组和治疗组。对照组予口服盐酸多奈哌齐,治疗组在对照组治疗的基础上予"养髓益智"组穴针刺,两组在治疗前,治疗4 w,治疗8 w后进行MoCA量表、MMSE量表、血管性痴呆中医辩证量表(SDSVD)(肾精亏虚型)疗效评估,并比较疗效差异。结果:(1)对两组患者治疗后量表(MoCA、MMSE、SDSVD)评分评估疗效:治疗组的疗效优于对照组(P0.05),治疗组总有效率分别为96.6%、93.3%、96.7%,对照组总有效率分别为76.7%、60%、60%,经卡方检验治疗组疗效显著优于对照组(P0.05)(2)中医肾精亏虚症候方面,治疗组肾精亏虚症候变化明显高于对照组,尤其在腰膝酸软、耳鸣、夜尿多等方面变化显著(P0.01)。结论:"养髓益智"组穴在针刺治疗肾精亏虚型VCI患者时,能明显改善认知能力及临床症状,提高生活质量。

Clinical Observation of Acupuncture by Enriching Renal Essence and Improving Intelligence in Group Acupoints for Vascular Cognitive Impairment (Deficiency of Kidney Essence)

To observe the clinical efficacy of acupuncture by enriching renal essence and improving intelligence in group acupoints tor vascular cognitive impairment (deficiency of kidney essence).Methods:sixty eligible patients were allocated and divided randomly into control group and treatment group,with 30 cases each.control group received Donepezil Hydrochloride Tablets,and the treatment group,acupuncture by enriching renal essence and improving intelligence in group acupoints in addition.Before the treatment,4 weeks after that,and 8 weeks after treatment,the simplified Montreal Cognitive Assessment (MoCA) score,Mini-mental State Examination (MMSE) and The Scale for differentiation of syndromes of vascular dementia (SDSVD) (deficiency of kidney essence) results of the two groups will be compared and assessed.Results:(1) Two groups after treatment by scale (MoCA,MMSE s,SDSVD) to assess efficacy:compared with the situation before treatment,the treatment group was better than the control group (P ＜ 0.05),total efficiency of the treatment group were 96.6％,93.3％,96.7％ respectively and the control group were 76.7％,60％,60％ respectively.by rank sum test of the two groups,treatment group was significantly better than the control group (P ＜ 0.05).(2) The treatment group was dramatically better than the control group on the deficency of kidney essence of TCM symptoms,the prominent change was about the soreness and weakness of waist and knees,tinnitus,nocturia (P ＜0.01).Conclusion:Acupuncture by enriching renal essence and improving intelligence in group acupoints can significantly improve cognitive function and clinical symptoms in patients with VCI,and improve the quality of life