中医解毒散结扶正法与调强放疗相结合治疗鼻咽癌临床疗效研究

目的:中西医结合即中医解毒散结扶正法与调强放疗相结合治疗鼻咽癌的临床疗效探讨.方法:选取我院2015年1月-2016年1月住院的鼻咽癌患者58例,随机分为观察组29例与对照组29例.对照组给予调强放疗:GTVnx及GTVnd剂量为68-72 Gy、66-70 Gy,CTV1和CTV2剂量分别为60-64 Gy和50-54 Gy.所有患者采用分割照射法,每周进行5次,共6～8w.观察组采用调强放疗的同时加用祖国医学的解毒散结扶正法治疗:调强放疗法同对照组,放疗期间同时服中药汤剂,每日一付,早晚分服.结果:治疗后,对比2组鼻咽癌患者的临床总有效率及毒副反应.观察组治疗总有效率为93.1％明显高于对照组的77.8％(P＜0.05);观察组毒副反应发生方面也显著低于对照组(P＜0.05).结论:中医解毒散结扶正法联合调强放疗能够提高鼻咽癌患者的临床治疗有效率,且降低毒副反应的发生.

Intensity Modulated Radiation Therapy (IMRT) of Traditional Chinese Medicine of Invigorating Vital Essence and Detoxification Fights the Clinical curative Effect of Combined Treatment of Nasopharyngeal Carcinoma Research

Objective:To combine traditional Chinese and western medicine is the traditional Chinese medicine of invigorating vital essence and detoxification fights intensity-modulated radiotherapy combined with the clinical efficacy of nasopharyngeal carcinoma (NPC).Methods:From January 2014 to December 2015 in the hospital of 58 patients with nasopharyngeal carcinoma,29 cases were randomly divided into observation group and control group in 29 cases.Intensity modulated radiation therapy (imrt) in the control group given:GTVnx and GTVnd dose is 68-72-Gy,72-70,CTV1 and CTV2 doses respectively for 60-64 Gy and 50-54 Gy.All of the patients using segmentation ZhaoSheFa,five times a week,a total of six to eight weeks.Observation group of intensity modulated radiation therapy (imrt) used at the same time combined with method of invigorating vital essence treatment:the motherland medicine detoxification fights intensity-modulated therapy with the control group,radiation medicine medicinal broth,at the same time during the day to pay,sooner or later points.Results:After treatment,compared two groups of clinical total effective rate and adverse reaction in patients with nasopharyngeal carcinoma (NPC).Treatment the total effective rate was 93.1％ observation group was obviously higher than that of control group 77.8％ (P ＜0.05);The observation group was significantly lower than control group the incidence of adverse reaction (P ＜ 0.05).Conclusion:Chinese medicine of invigorating vital essence joint detoxification fights intensity-modulated radiation therapy can improve the clinical treatment of patients with nasopharyngeal carcinoma (NPC) efficiently,and reduce the occurrence of adverse reaction.