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| Down’s综合征产前筛查假阳性与血清标志物测定值的关系分析 | |
| 引用本文： | 陶敏芳. Down’s综合征产前筛查假阳性与血清标志物测定值的关系分析[J]. 上海医学检验杂志, 2004, 0(3) |
| 作者姓名： | 陶敏芳 |
| 作者单位： | 上海交通大学附属上海市第六人民医院 上海200233 |
| 摘 要： | 目的 探讨Down’s综合征母血筛查假阳性病例的血清标志物测定值。方法 研究 2 0 0 0～ 2 0 0 2年中1341例三联筛查的病例 ,对确诊假阳性的病例回顾性分析其标志物的情况。结果 假阳性病例共 132例 ,其中游离雌三醇 (uE3)异常占 72 .7%。结论 单一uE3异常的阳性病例无意义 ,是造成筛查假阳性的主要原因 |
| 关 键 词： | Down’s综合征 血清标志物 产前筛查 假阳性 |
Analysis of the relationship between the false positive cases in Down''''s syndrome screening and their serum markers value |
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| TAO Minfang. Analysis of the relationship between the false positive cases in Down''''s syndrome screening and their serum markers value[J]. Shanghai Journal of Medical Laboratory Sciences, 2004, 0(3) | |
| Authors: | TAO Minfang |
| Affiliation: | TAO Minfang. Shanghai Sixth People's Hospital,Jiaotong University,Shanghai 200233,China |
| Abstract: | Objective To analyse the results of serum markers in false positive cases of maternal serum screening of Down's syndrome. Methods The study population was composed of 1 341 women subjected to triple markers screening from 2000 to 2002. The results of false positive cases were analysed retrospectively. Results There were 132 false positive cases, the ratio of abnormal uE3 was 72.7%. Conclusions Single abnormality of uE3 is not valuable, it is the main cause of false positive of screening. |
| Keywords: | Down's syndrome Serum marker Prenatal screening False positive rate |
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