血压昼夜变化与动脉硬化指数的关系

目的 探讨血压昼夜节律改变与动脉硬化的关系.方法 收集2004～2008年行24 h动态血压监测的住院患者的动态血压数据及相关资料,并进行统计分析.结果 在调整性别、年龄、降压治疗、24 h脉率及平均动脉压前后,242例患者中非杓型(n=103)、反杓型(n=42)和超杓型(n=12)与杓型患者(n=85)相比,动态动脉硬化指数和24 h脉压均显著升高,而年龄、血糖、尿酸、总胆固醇及甘油三酯等差异无显著性(P>0.05).结论 血压昼夜节律的改变与动脉硬化相关.

Relationship Between Circadian Blood Pressure Variation and Arterial Stiffness Index

Aim To investigate the relationship between circadian rhythm of blood pressure and arterial stiffness. Methods We collected and analyzed ambulatory and clinical data in inpatients of a comprehensive department during 2004-2008 in the Affiliated Hospital of Dali University. Results In 242 inpatients,before and after adjustment of age,sex,antihypertensive treatment,24 h pulse rate and mean arterial blood pressure,compared with dippers(n=85),non-dippers(n=103),reverse dippers(n=42) and extreme dippers(n=12) had a significantly higher ambulatory arterial stiffness index and 24 h pulse pressure.There was no significant difference in age,plasma glucose,uric acid,total cholesterol and triglyceride among four groups(P>0.05). Conclusion Abnormal circadian rhythm of blood pressure was associated with arterial stiffness.