Conjunctival involvement in Churg-Strauss syndrome |
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| Authors: | C L Shields J A Shields T I Rozanski |
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| Affiliation: | 1. Department of Clinical Immunology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia;2. Department of Clinical Immunology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia;3. Department of Neuropathology, PathWest Laboratory Medicine, Royal Perth Hospital, Perth, Western Australia, Australia;1. Orthopaedic Trauma Institute, Department of Orthopaedic Surgery, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA, USA;2. Sunnybrook Health Sciences Centre, Division of Orthopaedic Surgery, University of Toronto, Toronto, ON, Canada |
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| Abstract: | ![]()
A 64-year-old man had slowly progressive thickening of the bulbar and palpebral conjunctiva of the right eye, followed by signs and symptoms of an upper respiratory infection. A biopsy specimen of the conjunctival lesions demonstrated granulomatous inflammation with eosinophils compatible with a diagnosis of Churg-Strauss syndrome (asthma, eosinophilia, vasculitis, and granulomatous inflammation with eosinophils). Subsequently, fever, shortness of breath, moderate renal failure, and anemia developed. Therapy with systemic corticosteroids and cyclophosphamide was instituted, with resolution of the systemic and ocular manifestations. |
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