Plasma uric acid in patients receiving anticonvulsant monotherapy |
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| Authors: | H A Ring A J Heller W J Marshall A L Johnson E H Reynolds |
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| Affiliation: | Department of Neurology, King's College Hospital, London, U.K. |
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| Abstract: | In newly diagnosed adult patients with epilepsy followed prospectively on monotherapy, carbamazepine and phenytoin were associated with a fall in plasma uric acid, but sodium valproate and phenobarbitone were associated with a rise in plasma uric acid. The mechanisms and significance of these findings are discussed. |
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