Metastatic uterine leiomyosarcoma to the submandibular gland |
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| Authors: | Marco Ferreira Anais Malpica |
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| Affiliation: | 1. Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E., Lisboa, Portugal;2. Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA;1. Master Student in Dentistry (Stomatology), Department of Stomatology and Oral Pathology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil;2. Associate Professor, Department of Stomatology, School of Dentistry, Federal University of Ceará Sobral Campus, Sobral, Ceará, Brazil;3. Pathologist, Department of Pathology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil;4. Associate Professor, Department of Stomatology and Oral Pathology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil;5. Associate Professor, Department of Oral Pathology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil;1. Departments of Psychiatry, ?i?li Etfal Training and Education Hospital, Halaskargazi Avenue, Etfal Street, 34371 Istanbul Turkey;2. Department of Psychiatry, Bak?rkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey;3. Departments of Psychiatry, Medical School of Cerrahpasa, Istanbul, Turkey;1. Associate Professor, Director, Comprehensive Multiple Sclerosis Center, Thomas Jefferson University, Philadelphia, PA;2. President, Advanced Neurosciences Institute, President, NeuroNexus Center for Neurology Education and Research, Nashville, TN;3. President, Florida Society of Neurology, Medical Director, Neurologique, Ponte Vedra, FL;4. Associate Professor of Neurology, Director, Multiple Sclerosis, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;1. Department of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, Mich;2. Departments of Medicine and Public Health, University of Arizona, Tucson;3. Department of Research, St. Mary Mercy Hospital, Livonia, Mich |
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| Abstract: | ![]()
Metastasis of uterine leiomyosarcoma to the salivary glands is exceedingly rare. In this report, we present the clinicopathologic features of one such case. The patient was diagnosed with uterine leiomyosarcoma at age 58 years and was treated by hysterectomy only. The tumor was confined to the uterine body. The patient remained free of disease for 4 years and then developed a left submandibular mass. Imaging studies also showed lung involvement but no tumor in the abdomen or pelvis. The submandibular mass was resected; it had histologic and immunohistochemical features similar to those seen in the previous uterine leiomyosarcoma. After 7 months of follow-up, the patient is alive with disease, with progression of disease in the lungs despite receiving chemotherapy. |
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