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| 大黄清胃冲剂活性成分提取工艺的均匀设计优化选择 | |
| 引用本文： | 范国荣,胡晋红,徐萍,梁秉文,林梅,张正行,安登魁. 大黄清胃冲剂活性成分提取工艺的均匀设计优化选择[J]. 中成药, 2000, 22(5): 321-323 |
| 作者姓名： | 范国荣 胡晋红 徐萍 梁秉文 林梅 张正行 安登魁 |
| 作者单位： | 1. 第二军医大学附属长海医院,上海,200433 2. 中国人民解放军第四五四医院,江苏,南京,210001 3. 中国药科大学,江苏,南京,210009 |
| 摘 要： | 目的 探讨大黄清胃冲剂活性成分提取分离的优化工艺条件。方法 以游离蒽醌提取率为定量指标，通过４种生长黄煎煮方法的初步筛选，确定浸渍溶剂、浸渍时间、回流溶剂及回流时间为考察因素，并为Ｕ９（９＾６）均匀表设计试验。结果 大黄提取优化工艺条件为７０％乙醇浸润１４ｈ和回流提取８０ｍｉｎ。结论 工艺条件可以用于大黄清胃冲剂的生产制备。 |
| 关 键 词： | 大黄清胃冲剂 游离蒽醌 提取工艺 均匀设计 |
| 文章编号： | 1001-1528(2000)05-0321-03 |
| 修稿时间： | 1999-10-30 |
Optimal Selection of Extraction Process of Active Constituents in Dahuangqingwei Granules by Uniform Design |
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| FAN Guo-rong,HU Jin-hong,XU Ping,LIANG Bin-wen,LIN Mei,ZHANG Zhen-xing,AN Deng-kui. Optimal Selection of Extraction Process of Active Constituents in Dahuangqingwei Granules by Uniform Design[J]. Chinese Traditional Patent Medicine, 2000, 22(5): 321-323 | |
| Authors: | FAN Guo-rong HU Jin-hong XU Ping LIANG Bin-wen LIN Mei ZHANG Zhen-xing AN Deng-kui |
| Abstract: | Objective: To study the optimal extraction process for active constituents of Dahuang qingwei Granules.Methods: The main influence factors including soaking solvent,soaking time, refluxing solvent and refluxing time were defined based on primary selection of four pre designed extraction methods for Radix et Rhizoma Rhei, with the extraction efficiency of free anthraquinones as an index,and the U9(96) uniform test table was used to arrange sequent experiments. Results: The optimal extraction process consists of soaking for 14 hours with 70% ethanol, refluxing and extracting for 80 minutes. Conclusion: The experimental method is suitable to the productive preparation of Dahuangqing wei Granules. |
| Keywords: | Radix et Rhizoma free anthraquinones extraction process uniform design |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |