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Male Sexual Function After Pediatric Kidney Transplantation—A Cross-sectional Nationwide Study
Institution:1. IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy;2. Department of PD, Movement Disorder and brain Injury rehab, Moriggia Pelascini Hospital, Gravedona, Italy;3. Istituto Italiano di Sessuologia Scientifica, Rome, Italy;4. Padre Pio Foundation and Rehabilitation Centers, San Giovanni Rotondo, Foggia, Italy;1. Emory University, School of Medicine, Atlanta, GA, USA;2. Emory University, Rollins School of Public Health, Atlanta GA, USA;3. Center for Research and Evaluation, Kaiser Permanente Georgia, Atlanta, GA, USA;4. Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA;5. The Rockway Institute, Alliant International University, San Francisco, CA, USA;6. Georgia State University, School of Public Health, Department of Health Policy and Behavioral Sciences, Atlanta GA, USA;7. Mid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, Rockville, MD, USA;8. Division of Research, Kaiser Permanente, Northern California, Oakland, CA, USA;9. The Atlanta Veteran Affairs Medical Center, Atlanta GA, USA;1. Department of Psychology, Valparaiso University, Valparaiso IN, USA;2. Premature Ejaculation Help, Montreal, CA, USA;1. Department of Urology, Xijing Hospital, Fourth Military Medical University, Xi''an, China;2. Department of Andrology, Xi''an Daxing Hospital, Shaanxi University of Chinese Medicine, Xi''an, China;3. Assisted Reproduction Center, Northwest Women''s and Children''s Hospital, Xi''an, China;4. Department of Urology, Xi''an Daxing Hospital, Shaanxi University of Chinese Medicine, Xi''an, China;5. St. George''s University School of Medicine, West Indies, Grenada;6. Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy;1. Department of Psychiatry, Cerrahpa?a School of Medicine, Istanbul University-Cerrahpa?a, Istanbul, Turkey;2. Department of Psychiatry, Gaziosmanpa?a Taksim Training and Research Hospital, Istanbul, Turkey;3. Department of Psychiatry, Nizip State Hospital, Gaziantep, Turkey;4. Department of Public Health, Ankara Y?ld?r?m Beyaz?t University, Ankara, Turkey
Abstract:BackgroundData on adult sexual functioning after kidney transplantation (KTx) during childhood or adolescence are scarce.AimTo assess the long-term sexual and psychosocial quality of life after pediatric KTx.Methods29 young men (median age 27.1 years) were examined 18.7 years (median) after KTx. 56 age-matched healthy men (median age 30.0 years) served as controls.OutcomeWe studied the influence of sociodemographics, previous renal replacement therapy, current reproductive hormonal serum levels, testicular size, and data on several validated mental and physical questionnaires on participants' Derogatis Interview for Sexual Functioning self-report scores.ResultsThe KTx recipients had significantly poorer sexual functioning than their healthy peers. KTx men had less frequent sexual activity with a partner (P = .03) and poorer orgasms (P = .002) than the controls but no erectile dysfunction (P = .5).Clinical implicationsDepressive symptoms, relationship status, and longer dialysis duration predicted poor adult sexual functioning in KTx recipients, whereas age at transplantation or at the time of the study did not.Strengths & LimitationsThis study contributes extended follow-up data to the very scarce literature on adult sexual functioning in pediatric KTx recipients. Relatively small population and low participation rate limit the comprehensive data interpretation in a population-based cohort of male KTx recipients.ConclusionSexual functioning is often impaired in young men after pediatric KTx, emphasizing the need for long-term monitoring of sexual health and sexuality as important dimensions of quality of life.Tainio J, Jahnukainen T, Jalanko H, et al. Male Sexual Function After Pediatric Kidney Transplantation—A Cross-sectional Nationwide Study. J Sex Med 2020;17:2104–2107.
Keywords:Children and Adolescents  Kidney Transplantation  Late Effects  Long-Term Outcome  Sexual Function
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