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| 脑瘫患儿应用脐血间质干细胞的临床安全性研究 | |
| 引用本文： | 吴芳,杨万章,张敏,杨佳勇,盛佑祥,赵宁,梁豪文,唐映. 脑瘫患儿应用脐血间质干细胞的临床安全性研究[J]. 中西医结合心脑血管病杂志, 2008, 6(12) |
| 作者姓名： | 吴芳 杨万章 张敏 杨佳勇 盛佑祥 赵宁 梁豪文 唐映 |
| 作者单位： | 1. 广东医学院附属深圳南山医院,518052 2. 广东省深圳市第九人民医院 |
| 摘 要： | 目的评价人脐血间质干细胞临床应用于脑瘫患儿的安全性。方法脐血间质干细胞鞘内和静脉注射治疗44例脑瘫患儿,对治疗前、治疗后脑瘫患儿的血常规、肝肾功能、电解质、血清酶学、血清免疫蛋白及补体、T细胞亚群进行对比研究。结果患儿的血常规、肝肾功能、电解质、细胞与体液免疫各项指标治疗前后的检测结果无统计学意义(P>0.05)。结论脐血源神经干细胞的临床应用是安全可行的。 |
| 关 键 词： | 脑瘫 安全性 脐血间质干细胞 |
Umbilical Cord Blood Mesenchymal Stem Cell Transplantation for Cerebral Palsy Patients |
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| Wu Fang,Yang Wanzhang,Zhang Min,et al. Umbilical Cord Blood Mesenchymal Stem Cell Transplantation for Cerebral Palsy Patients[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2008, 6(12) | |
| Authors: | Wu Fang Yang Wanzhang Zhang Min et al |
| Affiliation: | Shenzhen 518052 |
| Abstract: | Objective To explore the safety of transplantation of umbilical cord blood mesenchymal stem cell(UCB-MSCs) for patients(pts) with cerebral palsy(CP).Methods Forty-four pts with CP were treated by transplanting UCB-MSCs.The blood routine indices,the liver and renal function,electrolytes,the serum enzyme,serum immunoglobulins,complements and T-lymphocytes subsets were tested pre-and post-treatment.Results There was no statistical significance in the data tested in pts pre-and post-treatment(P>0.05).Conclusion The transplantation of UCB-MSCs for pts with CP was safety. |
| Keywords: | cerebral palsy safety umbilical cord blood mesenchymal stem cell |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |