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抗生素对老年肺部感染患者粪便大肠埃希菌耐药性的影响
引用本文:顾小军,吴玉强,戴群,殷国庆. 抗生素对老年肺部感染患者粪便大肠埃希菌耐药性的影响[J]. 东南大学学报(医学版), 2001, 20(2): 100-102
作者姓名:顾小军  吴玉强  戴群  殷国庆
作者单位:东南大学医学院附属南京第二医院,;东南大学医学院附属南京第二医院,;东南大学医学院附属南京第二医院,;东南大学医学院附属南京第二医院,
摘    要:目的 :观察抗生素对粪便大肠埃希菌耐药性的影响。方法 :对 2 4例医院老年肺炎患者于抗生素治疗前、治疗1周内、停药 1个月后作粪便培养以动态监测大肠埃希菌的耐药性 ,并分析其耐药情况。结果 :粪便大肠埃希菌在用药 1周内其耐药性增强 ,停药 1个月后敏感性部分恢复 ,但不能完全消失。结论 :抗生素能明显增强大肠埃希菌的耐药性 ,应尽量避免全身用药 ,减少耐药性的扩散。

关 键 词:抗生素  耐药  大肠埃希菌  老年人
文章编号:1001-7275(2001)02-0100-03
修稿时间:2000-09-21

The influence of antibiotics on the drug resistance of Escherichia coli in stool of senile patients
GU Xiao jun,WU Yu qiang,DAI Qun,YIN Guo qing. The influence of antibiotics on the drug resistance of Escherichia coli in stool of senile patients[J]. Journal of Southeast Univ: Medical Sci Ed, 2001, 20(2): 100-102
Authors:GU Xiao jun  WU Yu qiang  DAI Qun  YIN Guo qing
Abstract:Objective To observe the effect of antibiotics on the drug resistance of Escherichia coli in stool of senile patients antibiotics.Methods Monitored 24 pneumonia patients in hospital who used antibiotics and cultured their stool before treated,within a week of treatment and a month after stopping to gain the state of resistance Escherichia coli ,and analysed the data.Results The resistance of Escherichia coli is enhanced within a week and the sensitiveness recovered partly after stopping antibiotics,but the resistance couldn't disappear completely.Conclusion The results show that antibiotics can enhance the resistance of Escherichia coli ,it is necessary to avoid systemic use so as to decrease the diffusion of resistance.
Keywords:antibiotic  resistance  Escherichia coli  aged
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