局部注射醋酸曲安奈德致迟发过敏反应1例

糖皮质激素是临床上常用的抗炎、抗过敏药物。糖皮质激素过敏是一类由糖皮质激素作为变应原引起的过敏反应，在临床上并不多见，其超敏反应的临床表现无特异性。现报道1 例湖南中南大学湘雅口腔医院收治的口腔扁平苔藓患者，在接受舌部局部注射醋酸曲安奈德后出现迟发性过敏反应。患者表现为舌部黏膜局部糜烂、出血、疼痛，予以双氯芬酸钠缓释片口服、碳酸氢钠注射液漱口、康复新液含服后过敏症状缓解。临床上需进一步加深对此类药物的认识，对考虑糖皮质激素过敏的患者需要尽快切断过敏原，并根据超敏反应类型进行相应的处理，从而改善治疗效果。

A case of delayed allergic reaction caused by local injection of triamcinolone acetonide

Glucocorticoid is a commonly used anti-inflammatory and anti-allergic drug in clinic.Allergic reactions caused by glucocorticoids are rare in clinic. Glucocorticoid allergy is atype of allergic reaction caused by glucocorticoid as an allergen, and its clinicalmanifestations of hypersensitivity are not specific. Here we reported a case of an allergicreaction in patients with oral lichen planus who received submucosal injection oftriamcinolone acetonide in the tongue. The patient showed local erosion, bleeding, and painin the mucous membrane of the tongue in the Xiangya Stomatological Hospital, CentralSouth University. The allergic symptoms were relieved after the patient was givendiclofenac sodium sustained-release tablets, sodium bicarbonate injection for gargle, andKangfuxin liquid.It is the clinical need to further deepen the understanding of glucocorticoidallergy. The allergens should be cut off as soon as possible, and the corresponding treatmentis performed according to the type of hypersensitivity reaction, thereby improving thetherapeutic effect.