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清热合剂的解热抗炎作用
引用本文:何晓静,肇丽梅. 清热合剂的解热抗炎作用[J]. 广东药学院学报, 2006, 22(1): 73-75
作者姓名:何晓静  肇丽梅
作者单位:中国医科大学附属第二医院,药剂科,辽宁,沈阳,110004;中国医科大学附属第二医院,药剂科,辽宁,沈阳,110004
摘    要:
目的研究清热合剂的解热、抗炎作用。方法分别采用2,4-二硝基苯酚致热大鼠模型、内毒素致热家兔模型、二甲苯致小鼠耳肿胀及蛋清致大鼠足肿胀模型,研究清热合剂的解热、抗炎作用。结果清热合剂可以降低由2,4-二硝基苯酚引起的大鼠体温升高及内毒素引起的家兔体温升高,抑制二甲苯致小鼠耳肿胀及蛋清致大鼠足肿胀。结论清热合剂具有解热、抗炎作用。

关 键 词:清热合剂  解热作用  抗炎作用
文章编号:1006-8783(2006)01-0073-03
收稿时间:2005-08-30
修稿时间:2005-10-31

The Fever-relieving and Anti-inflammatory effects of Qing-Re mixture
HE Xiao-jing,ZHAO Li-mei. The Fever-relieving and Anti-inflammatory effects of Qing-Re mixture[J]. Academic Journal of Guangdong College of Pharmacy, 2006, 22(1): 73-75
Authors:HE Xiao-jing  ZHAO Li-mei
Affiliation:The Second Affiliated Hospital of China Medical University, Shenyang 110004, China
Abstract:
Objective To investigate the fever-relieving and anti-inflammatory effects of Qing-Re mixture(QR) for oral use.Methods Animal models of ear edema induced by xylene in mice,paw edema induced by egg white and fever induced by 2,4-dinitrophenol in rats and endotoxin in rabbits were made,the fever-relieving and anti-inflammatory effects of Qing-Re mixture were studied.Result Qing-Re mixture showed a marked suppressive effects on ear edema induced by xylene in mice,paw edema induced by egg white and fever induced by 2,4-dinitrophenol in rats and endotoxin in rabbits.Conclusion Qing-Re mixture has the anti-inflammation and fever-relieving effects.
Keywords:Qing-Re mixture  fever-relieving effect  anti-inflammatory effect
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