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高频超声监测舒降之干预颈动脉粥样硬化的临床研究
引用本文:周青,郭瑞强,孙彬,郝力丹.高频超声监测舒降之干预颈动脉粥样硬化的临床研究[J].中国医学影像技术,2003,19(6):685-686.
作者姓名:周青  郭瑞强  孙彬  郝力丹
作者单位:武汉大学人民医院超声科,湖北武汉,430060
摘    要:目的 评价舒降之对颈动脉粥样硬化病变的影响。方法高频超声监测随访 2年舒降之治疗组的颈动脉管壁改变。结果 舒降之治疗 2年后IMT和IMT横截面积总体呈下降趋势 ,IMT变化速度为年下降 0 .0 3mm。颈动脉超声分型的变化无显著意义 ,但粥样斑块分型于随访前后发生了一定的变化 ,差异显著 (P <0 .0 5 )。结论降脂药物能减轻甚至逆转早期动脉壁粥样病变 ,高频超声是首选的无创监测手段。

关 键 词:舒降之  高频超声  颈动脉粥样硬化  IMT  监测  分型  干预  下降趋势  变化速度  减轻
文章编号:1003-3289(2003)06-0685-02
收稿时间:2002/10/3 0:00:00
修稿时间:2002年10月3日

High-Frequency Ultrasonic Assessment of Carotid Atherosclerotic Lesions
Involved with Cholesterol-Lowering Therapy
ZHOU Qing,GUO Rui-qiang,SUN Bin and HE Li-dan.High-Frequency Ultrasonic Assessment of Carotid Atherosclerotic Lesions
Involved with Cholesterol-Lowering Therapy[J].Chinese Journal of Medical Imaging Technology,2003,19(6):685-686.
Authors:ZHOU Qing  GUO Rui-qiang  SUN Bin and HE Li-dan
Institution:Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan 430060,China;Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan 430060,China;Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan 430060,China;Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan 430060,China
Abstract:Objective To investigate the effects of simvastatin on carotid atherosclerotic lesions. Methods Simvastatin treating patients were followed up 2 years by high frequency ultrasound examination.Results After 2 years treatment, the IMT and IMT area of common carotid decreased significantly ( P <0.01),and IMT decreased at a speed of 0.03mm/year. The carotid wall ultrasonic classification changed non statistically, while the plaques in carotid changed significantly ( P < 0.05 ) after 2 year therapy. Conclusion Ultrasonic examination is the first hand choice of monitoring the retrogression and progression of the atherosclerosis involved with drug therapy non invasively.
Keywords:Carotid artery  Atherosclerosis  Simvastatin  High  frequency ultrasound
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