| 低剂量辐射诱导蛋白对正常人外周血淋巴细胞亚群的刺激效应 |
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| 引用本文： | 吕兑财,苏燎原. 低剂量辐射诱导蛋白对正常人外周血淋巴细胞亚群的刺激效应[J]. 航天医学与医学工程, 2003, 16(3): 165-167 |
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| 作者姓名： | 吕兑财 苏燎原 |
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| 作者单位： | 航天医学工程研究所,北京100094;苏州大学核医学院,江苏苏州,215007 |
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| 摘 要： | 目的 探讨低剂量辐射(LDR)诱导蛋白对淋巴细胞亚群功能的影响。方法 观察LDR诱导蛋白对单克隆抗体铺皿法—直接法分离出的淋巴细胞亚群CD4、CD8、CDl9细胞转化功能的影响。结果 经LDR诱导蛋白作用后,亚群细胞14C—TdR掺入值增高,分别为对照组的118．23％、115．18％和121．62％。结论 LDR诱导蛋白能不同程度地刺激CD4、CD8、CDl9细胞DNA合成。
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| 关 键 词： | 低剂量辐射 诱导蛋白 淋巴细胞亚群 刺激效应 |
| 文章编号： | 1002-0837(2003)03-0165-03 |
| 修稿时间： | 2002-06-10 |
Stimulative Effects of LDR Induced Proteins on Human Peripheral Blood Lymphocyte Subsets |
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| Dui-cai Lu,Liao-yuan Su. Stimulative Effects of LDR Induced Proteins on Human Peripheral Blood Lymphocyte Subsets[J]. Space Medicine & Medical Engineering, 2003, 16(3): 165-167 |
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| Authors: | Dui-cai Lu Liao-yuan Su |
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| Affiliation: | Institute of Space Medico-Engineering, Beijing, China. |
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| Abstract: | Objective: To find effects of low dose radiation (LDR) induced proteins on lymphocyte subsets. Method: Stimulative effects of LDR-induced proteins on human peripheral blood lymphocyte subsets were studied. Result: The 14C-TdR incorporation in CD4, CD8, CD19 cells increased by 118.23%, 115.18% and 121.62% respectively compared with control group. Conclusion: LDR induced proteins can stimulate proliferation of CD4, CD8 and CD19 cells. |
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| Keywords: | low dose radiation induced proteins lymphocyte subsets stimulating effects |
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