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Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy |
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| Authors: | Suganthalakshmi Balasubbu Periasamy Sundaresan Anand Rajendran Kim Ramasamy Gowthaman Govindarajan Namperumalsamy Perumalsamy J Fielding Hejtmancik |
| Affiliation: | (1) Aravind Medical Research Foundation, Dr. G. Venkataswamy Eye Research Institute, Aravind Eye Hospital, #1, Anna Nagar, Madurai, 625 020, India;(2) Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, USA;(3) Retina Clinic, Aravind Eye Hospital, #1, Anna Nagar, Madurai, 625 020, India;(4) Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, 5635 Fisher's Lane, Rockville, MD 20852, USA |
| Abstract: | BackgroundDiabetic retinopathy (DR) is classically defined as a microvasculopathy that primarily affects the small blood vessels of the inner retina as a complication of diabetes mellitus (DM).It is a multifactorial disease with a strong genetic component. The aim of this study is to investigate the association of a set of nine candidate genes with the development of diabetic retinopathy in a South Indian cohort who have type 2 diabetes mellitus (T2DM). |
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