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Expression of thymidylate synthase determines the response of gastric cancer patients undergoing gastrectomy to 5-fluorouracil-based adjuvant chemotherapy |
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| Authors: | Chun-Nan Yeh Shih-Ming Jung Tsung-Wen Chen Tsann-Long Hwang Yi-Yin Jan Miin-Fu Chen |
| Affiliation: | (1) Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan, Republic of China;(2) Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan, Republic of China |
| Abstract: | PurposeWe investigated whether the intensity of thymidylate synthase (TS) staining in tissue samples obtained from gastric cancer (GC) patients undergoing gastrectomy could predict response to 5-FU-based adjuvant chemotherapy after gastrectomy. |
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