蒲黄对家兔实验性急性心肌梗塞的影响

本文报告用家兔左室支动脉结扎形成急性心肌梗塞模型,以硝基四氮唑蓝(N-BT)作大体标本染色及组织学检查来评价蒲黄的抗梗塞作用。结果表明,蒲黄可以限制梗塞的范围。其疗效与异搏定相近似。值得推荐临床进一步观察。

Effect of Typha Angustata on Experimental Acute Myocardial Infarction in Rabbits

In traditional Chinese medicine Typha angustata(TA)was stated to possess the function of promoting tissue blood perfusion and eliminating circulatory stasis.It has the function of improving microcirculation, inhibiting-exudation effect and reducing aggregation of platelets.It may be used to protect myocardial cells from ischemic injuries or infarction. Acute myocardial model was produced by ligation of the left ventricular branch of coronary artery of the rabbit,and effects of TA treatment were observed and compared with those of verapamil,and normal saline and blank control. N-BT staining was used to identify the extent of infarction and the injured myocardium was examined histologically in detail.The results showed that TA treatment can significantly reduce the size of infarction as verapamil does.It is suggested that TA might be introduced to further clinical trials.