10d序贯疗法治疗幽门螺旋杆菌感染患儿的疗效分析

目的分析10d序贯疗法治疗幽门螺旋杆菌感染患儿的临床疗效。方法选择2010年1月～2011年6月某院收治的幽门螺旋杆菌感染患儿67例,采用随机数字表法随机分为观察组34例和对照组33例。观察组患者采用10d序贯疗法,对照组患者采用7d三联疗法。结果观察组患者的疗效优于对照组,差异有统计学意义(H=9.837,P=0.029);观察组患者的Hp根除率高于对照组(χ2=4.941,P=0.026);两组患者的不良反应发生率比较,差异无统计学意义(χ2=0.165,P=0.684)。结论 10d序贯疗法是治疗幽门螺旋杆菌感染患儿的理想方案,安全性好,Hp根除率高。

Clinical analysis of 10 day sequential therapy for Helicobacter pylori infection children

OBJECTIVE To analyze the curative effect of 10 day sequential therapy of Helicobacter pylori infection children.METHODS 67 Helicobacter pylori infection children were selected from January 2010 to June 2011 in our hospital,and they were randomly divided into the observation group with 34 cases and control group with 33 cases by random number table.The observation group were treated with 10 day sequential therapy,patients in the control group received 7 day triple therapy.RESULTS The treatment effect of observation group was more effective than control group,there was significant difference between the two groups(H = 9.837,P = 0.029);Hp eradication rate in the observation group were higher than control group(χ2 = 4.941,P = 0.026);Compared the incidence of adverse reactions between two groups of patients,there was significant difference between the two groups(χ2 = 0.165,P = 0.684).CONCLUSION 10 day sequential therapy were the ideal treatment plan of Helicobacter pylori infection children,which is good safety and has high rate of Hp eradication.