消旋卡多曲颗粒联合蒙脱石散治疗婴幼儿轮状病毒肠炎的疗效分析

目的观察消旋卡多曲颗粒联合蒙脱石散治疗婴幼儿轮状病毒肠炎的临床疗效。方法 2009年3月～2010年3月,120例轮状病毒肠炎患儿随机分为两组,观察组60例给予消旋卡多曲颗粒联合蒙脱石散治疗,对照组60例仅采用蒙脱石散治疗,对比观察两组的临床疗效以临床指标的变化。结果观察组的总有效率为86.7%,明显高于对照组的71.7%(P﹤0.05);并且,观察组的止吐时间、脱水纠正时间、大便次数正常时间和大便性状正常时间均明显短于对照组(P﹤0.05)。结论消旋卡多曲颗粒联合蒙脱石散对婴幼儿轮状病毒肠炎进行治疗,能够明显提高临床疗效,安全性高,值得临床推广应用。

Analysis on the effect of racecadotril particles combined with montmorillonite powder in treatment of infants with rotavirus enteritis

OBJECTIVE To observe the effect of racecadotril particles combined with montmorillonite powder in treatment of infants with rotavirus enteritis.METHODS From March 2009 to March 2010,120 infants with rotavirus enteritis were divided into two groups,of which observation group(60 cases)was treated with racecadotril particles combined with montmorillonite powder and control group(60 cases)was only treated with montmorillonite powder.The clinical effect and changes between the two groups were compared.RESULTS The total effective rate in observation group was 86.7%,which was significantly higher than that in control group with 71.7%(P﹤0.05).The disappear time of coughing,wheezing,crackles and hospitalization time of observation group were significantly shorter than those in control group(P﹤0.05).The antiemetic time,and time of dehydration correction,stool frequency and stool properties were significantly shorter than those in control group(P﹤0.05).CONCLUSION Racecadotril particles combined with montmorillonite powder in treatment of infants with rotavirus enteritis can enhance the effect,and have high safety,which can be applied in clinic.