内镜下氩离子凝固术治疗成熟型疣状胃炎35例临床分析

目的探讨内镜下氩离子凝固术(APC)在成熟型疣状胃炎中的治疗价值。方法35例成熟型疣状胃炎患者行APC治疗,氩气流量设定为2L/min,功率40～60W,灼除所有疣状病灶。术后给予奥美拉唑治疗。1个月后随访及胃镜复查。结果35例共146枚成熟型疣状胃炎病灶经APC治疗灼除,治疗次数根据病灶大小决定,平均每枚病灶治疗时间为3.9s(2￣6s)。所有患者未出现出血、穿孔等并发症。随访发现31例患者(88.6%)临床症状消失,内镜显示隆起病灶平伏,黏膜炎症明显改善。4例(11.4%)黏膜炎症改善,但仍有消化道症状。结论内镜下APC治疗成熟型疣状胃炎是一种安全、有效的方法。

Clinical value of argon plasma coagulation (APC) on mature verrucosa gastritis

[Objective] To assess the efficacy of argon plasma coagulation (APC) in the treatment of mature verrucosa gastritis. [Methods] 35 patients with mature verrucosa gastritis diagnosed by endoscopy and biopsy underwent APC therapy. Argon flow rate was 2 L/min and APC power ranged from 40 W to 60 W. After APC treatment, all patients received omeprazole therapy for two weeks. Clinical follow-up and another endoscopic examination were performed one month later. [Results] 146 verrucous lesions in 35 patients were ablated through APC therapy. Ablating frequency depended on the extent of lesions and the average time of treatment was 3.9 s (2~6 s). None of complications including bleeding or perforation happened. At the one month follow up, 31 patients (88.6%) had no symptom and endoscopic examination indicated that verrucous lesions became flatten and mucosal inflammation improved markedly. 4 patients (11.4%) still had digestive symptoms and endoscopic examination show slight or moderate improvement. [Conclusions] APC therapy is an effective and safe method for mature verrucosa gastritis.