肝硬变病人血清幽门螺杆菌抗体检测的临床意义

目的 探讨肝硬变病人幽门螺杆菌（Hp)的感染情况及临床意义。方法 应用ELISA法检测肝硬变病人血清Hp抗体。结果 275例肝硬变病人血清Hp抗体阳性195例（70.91%)，正常对照组135例，血清Hp抗体阳性53例（39.26%)，两组比较差异有显著意义（P＜0.01)。且肝功能愈差，Hp抗体阳性率愈高。对HBsAg阳性和HBsAg阴性肝硬变病人血清Hp抗体阳性率比较，发现前者高于后者（P＜0.01)。结论 肝硬变病人Hp感染率高，在治疗肝硬变时应及时清除Hp。

The clinical significance of anti-helicobacter pylori IgG detection in patients with liver cirrhosis

Objective To evaluate the prevalence and clinical significance of anti-helicobacter pyloir(Hp)IgG in patients with liver cirrhosis.Methods The serum anti-Hp IgG was examined by ELISA.Results The serum anti-Hp IgG in 275 cases of liver cirrhosis and 135 healthy groups was detected.The positive rates were 70.91%(195/275)and 39.26%(53/275)respectively.There was signsificant difference in anti-Hp IgG positive rates between the liver cirrhosis and the healthy groups.And the worse liver function,the higher anti-Hp IgG positive rate,anti-Hp IgG positive rate in liver cirrhosis with HBsAg positive was significantly higher than that in liver cirrhosis with HBsAg negative.Conclusion The Hp infection rate in patients with liver cirrhosis were higher than that in healthy groups.Therefore,we should try to eradicate Hp as we treat the liver cirrhosis.