| 脑室出血后脑脊液中溶血磷脂酸及侧脑室联合腰大池引流对脑积水的防治 |
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| 引用本文： | 袁强,步星耀,孙彦熙,闫兆月,马春晓,屈鸣麒.脑室出血后脑脊液中溶血磷脂酸及侧脑室联合腰大池引流对脑积水的防治[J].中国现代医学杂志,2015,25(14). |
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| 作者姓名： | 袁强 步星耀 孙彦熙 闫兆月 马春晓 屈鸣麒 |
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| 作者单位： | 郑州大学人民医院神经外科,河南郑州,450003 |
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| 摘 要： | 目的 探讨脑室出血(IVH)后脑脊液中溶血磷脂酸(LPA)及侧脑室联合腰大池引流对脑积水的防治效果.方法 选取86例IVH患者随机分为两组.对照组患者仅行侧脑室外引流治疗;观察组患者则采用侧脑室联合腰大池外引流治疗,并定期测定两组患者脑脊液中LPA含量,观察其与IVH后脑积水的关系及临床安全性.结果 IVH后患者脑脊液的血液清除时间观察组明显短于对照组(t=4.893,P=0.006);对照组患者发病7和14d时脑脊液LPA含量显著高于观察组(t1=3.118,P=0.002;t2=2.910,P=0.036);对照组慢性脑积水的发生率明显高于观察组(X 2=4.807,P=0.028);所有IVH并发脑积水患者发病14d时脑脊液中LPA含量显著高于IVH后未并发脑积水患者(t=6.056,P=0.000);治疗期间两组患者均未出现严重并发症.结论 侧脑室联合腰大池外引流较单纯侧脑室外引流能够更有效防治IVH后脑积水的发生,这与其迅速降低IVH后脑脊液中LPA含量密切相关.
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| 关 键 词： | 脑室出血 脑积水 脑室外引流 腰大池外引流 溶血磷脂酸 |
Lysophosphatidic acid level of cerebrospinal fluid after intraventricular hemorrhage and external ventricular drainage combined with lumbar cistern drainage for prevention and treatment of hydrocephalus |
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| Qiang YUAN,Xing-yao BU,Yan-xi SUN,Zhao-yue YAN,Chun-xiao MA,Ming-qi QU.Lysophosphatidic acid level of cerebrospinal fluid after intraventricular hemorrhage and external ventricular drainage combined with lumbar cistern drainage for prevention and treatment of hydrocephalus[J].China Journal of Modern Medicine,2015,25(14). |
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| Authors: | Qiang YUAN Xing-yao BU Yan-xi SUN Zhao-yue YAN Chun-xiao MA Ming-qi QU |
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| Abstract: | |
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| Keywords: | intraventricular hemorrhage hydrocephalus external ventricular drainage lumbar cistern drainage lysophosphatidic acid |
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