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丘脑底核电刺激治疗帕金森病及其术后管理
引用本文:李鹏,王伟,钟琪,任海波,王兴,毛伯镛. 丘脑底核电刺激治疗帕金森病及其术后管理[J]. 中国神经精神疾病杂志, 2010, 36(9)
作者姓名:李鹏  王伟  钟琪  任海波  王兴  毛伯镛
作者单位:四川大学华西医院神经外科,成都,610041
摘    要:
目的探讨丘脑底核电刺激治疗帕金森病术后症状缓解特点,为提高术后患者管理质量提供依据。方法自2008年1月至2009年12月,共34例帕金森病患者于我院接受丘脑底核电刺激手术治疗,其中单侧植入3例,双侧植入31例。术后由神经内外科医师配合对患者进行患者管理。分别于患者首次开机、术后半年和1年时对患者进行UPDRS运动评分,并记录副反应发生情况。结果 34例患者手术顺利,术后平均随访10.6个月。所有患者术后均出现微毁损效应。患者在不服药状态下,术前、首次开机、术后半年和术后1年UPDRS运动评分分别为:46.8±8.9,20.1±9.7,23.1±9.4和22.3±8.9;刺激器打开并服药后,患者症状得到进一步缓解。1例患者术后发生皮肤感染,1例患者发生胸前囊袋积液,经妥善处理后症状控制。结论丘脑底核电刺激治疗帕金森病疗效肯定,高质量的术后患者管理是维持手术疗效的重要环节。

关 键 词:帕金森病  脑深部电刺激  患者管理

Subthalamic nucleus deep brain stimulation surgery for patients with Parkinson's disease and the post-operative management
LI Peng,WANG Wei,ZHONG Qi,REN Haibo,WANG Xing,MAO Boyong. Subthalamic nucleus deep brain stimulation surgery for patients with Parkinson's disease and the post-operative management[J]. Chinese Journal of Nervous and Mental Diseases, 2010, 36(9)
Authors:LI Peng  WANG Wei  ZHONG Qi  REN Haibo  WANG Xing  MAO Boyong
Affiliation:LI Peng,WANG Wei,ZHONG Qi,REN Haibo,WANG Xing,MAO Boyong.Department of Neurosurgery,West China Hospital of Sichuan University,#37 Guoxue Alley,Chengdu 610041,China
Abstract:
Objective To improve the quality of post-operative patients management by analyzing the characteristics of the syndromes remission after the subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson's disease.Methods There were thirty-four patients receiving the STN-DBS from January 2008 to December 2009 at our DBS center.Thirty-one patients received,Bilateral DBS was performed in thrity-one patients and unilateral DBS in three.The post-operative management of the patients was accompli...
Keywords:Parkinson's disease Deep brain stimulation Patient management  
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