黄体不健的生殖内分泌变化

黄体不健是不孕症的重要原因之一。本文对52例黄体不健者采用放射免疫法测定其早卵泡期血请FSH、LH、PRL、E_2和黄体中期血清PRL、E_2,P_0水平,并与正常对照组进行比较。结果表明:黄体不健组早卵泡期FSH、LH、E_2及黄体中期P_0水平较正常对照组低,而PRL水平则高于正常对照组,其差别均有显著或非常显著性意义(P<0.05或P<0.01)。由此说明,黄体不健与卵泡发育障碍有关。因而认为对黄体不健的治疗,如果采用补充黄体酮的方法仅是“治标”,而促进卵泡发育成熟才是“治本”。并认为中医药的周期疗法可能为此打开一条有效途径。

Reproductive Eudocrine Changes in Inadequate Corpus Luteum

Inadequate corpus luteum is a major cause of infertility. In this paper, serum FSH, LH, PRL and E_2 in early follicular phase and PRL, E_2 and P_0 in middle luteal phase were studied by radioimmunoassay in 52 cases of corpus luteum insufficiency. Compared with the normal control group, there appeared a lower level of FSH, LH and E_2 in early follicular phase and lower P_0 in middle luteal phase, but a higher PRL level (P<0.05 or 0.01). This indicated that inadequate corpus luteum was relative to follicular maturation disorder. Therefore it is considered that for inadequate corpus luteum, to supplement progesterone is only a symptomatic treatment, while to promote fallicular maturation is the causative treatment.