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Effects of gallium and lanthanum on experimental tumor growth
Authors:L J Anghileri
Affiliation:1. Departamento de Química Inorgánica, Facultad de Química, Universidad Nacional Autónoma de México C.U., Coyoacán, Ciudad de México 04510, Mexico;2. Centro de Investigación en Alimentación y Desarrollo, A.C., Unidad Mazatlán en Acuicultura y Manejo Ambiental, Avenida Sábalo Cerritos s/n, Mazatlán, Sinaloa 82100, Mexico;1. Laboratory of studies of the host-parasite relationship, Tropical Pathology and Public Health Institute, Federal University of Goias. Brazil;2. Laboratorio de Biologia del Citoesqueleto, Departamento de Microbiologia y Parasitologia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico (UNAM), México, DF 04510, Mexico;3. Laboratorio Central de Microscopía, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (IPN), DF 11340, México
Abstract:
The effects of gallium and lanthanum compounds on DS sarcoma growth were studied. Under the stated experimental conditions gallium showed no tumor inhibition while lanthanum did. The probable mechanisms of action which explain this behavior are discussed on the basis of their pharmacological properties (calcergens) and of the influence of treatment procedure.
Keywords:
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