速冻玻璃化储存异体皮的临床应用

目的：分析和总结自1987年以来速冻玻璃化储皮临床应用情况。方法：搜集我科1987年至1999年使用速冻玻璃化储存的异体皮救治烧伤患者临床资料以及我科皮库储存异体皮国内使用情况，总结和分析速冻玻璃化储存异体皮的临床应用效果和异体皮的使用情况。结果：使用速冻玻璃化异体皮的烧伤患者平均烧伤面积为55.4%，其中平均Ⅲ度面积为30.9%，应用异体皮面积为3466～10208cm^2。采用速冻玻璃化保存的皮肤复温后其活力可达到新鲜皮肤的70%左右，该法保存的皮肤质地柔软、转红快、成活率高，存活期长，最长可在患者创面上成活2个月左右。术后异体皮成活率为95%。从1987年至1999年底我科皮库供全国各地18个省和3个自治区的48个市，8个县的108家各级医院冷冻异体皮使用，包括我科自用用，共使用皮肤面积达3604260cm^2。结论：采用速冻玻璃化储存的异体皮覆盖创面，仍是目前最有效、最方便、经济实惠的方法，使用异体皮进行烧伤的救治已经成为国内大多数医院普遍使用的一项救治措施。

The clinicalapplication of allograft skin preserved by vitrification

Objeetive..The purpose of this article is to analysis and sum up the clinical application of allograft skin preserved by vitrification. Methods.. The clinical data of burn patients from i987 to 1999 which were treated by allograft skin preserved by vitrification in our department, were collected. Then the clinical effects of allograft skin were summed up.Also the domestic utilization of allograft skin stored by our skin bank is analysised. Results: According to the burn patients treated by allograft skin preserved by vitrification, the average total burn area is 55. 4% ,the average Ⅲ°area is 30. 9% ,the average area of applied allograft skin is 3466cm2 to 10208cm2. The viability of thawed skin preserved by vitrification can reach to 70 % of fresh skin. The skin stored by this method can survive 2 months on the wound of burn patients. The survival of skin after grafting can reach to 95%。 Form 1987 to 1999 the cryopreserved skin of our skin bank have covered 108 different grades hospitals distributing 48 towns and 8 counties of 18 provinces and 3 municipalities. The total area of cryopreserved skin including those used by ourselves is 3604260cm2. Conclusion:The method of the coverage of burn wound with allogreft skin preserved by vitrification is still the most effective, convenient and economy one among the treatments of burn patients. ]Moreover this method is an universal treatment of burn in domestic hospitals.