Experimental study on interbody fusion with CFR/PEEK |
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| Authors: | SHIZhi-cai LiJia-shun JIALian-shun YUANWen HOUTie-sheng LI Ming ZHUXiao-dong |
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| Affiliation: | SHIZhi-cai,LiJia-shun,JIALian-shun,YUANWen,HOUTie-sheng,LI Ming,ZHUXiao-dong Department of Orthopedics,Changhai Hospital,Second Military Medical University,Shanghai200433,Chi na |
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| Abstract: | Objective:To studythebiocompatibilityof CFR/PEEKcompositeinbonetissueafterimplantedinlumbar intervertebralspaceandto evaluateitsroleintheinterbodyfusioncomparedwithallograftbone.Meth ods:Thirteen beagleswerechosenamongwhich7animalswereimplantedwiththedisk-likeCFR/PEEKcompositein thelumbar intervertebralspaceand6wereimplantedwithallograftbone.X-ray,QCTandhistologicalexaminationwereem-ployedat6,12,and24monthspostoperatively.Results:TheX-rayresultswereinconformitywiththatof QCT.His-tologicalexaminationshowedtheanteriorsofttissueof theimplantexhibiteda nonspecificforeignbodyreaction withconnectivetissuethebiomaterials.Carbonfragmentwereseeninthesurroundingtissueandsomeof thedebric werephagocytosedby foreignbodygiantcell.Histologicalexaminationof boneand materialshowednew bone growthalonetheholeof CFR/PEEKimplant.Con clu sion:CFR/PEEKhasexcellentbiocompatibilityto bonetissue. |
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| Keywords: | Polyetheretherketone composite fusion implant |
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