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| ＋Gz对颞下颌关节影响的动物实验模型 | |
| 引用本文： | 尹音,田慧颖,胡敏,马良,姚军,孙振宇,侯军,李传兵. ＋Gz对颞下颌关节影响的动物实验模型[J]. 军医进修学院学报, 2001, 22(4): 265-267 |
| 作者姓名： | 尹音 田慧颖 胡敏 马良 姚军 孙振宇 侯军 李传兵 |
| 作者单位： | 1. 空军总医院口腔科, 2. 中日友好医院口腔科, 3. 解放军总医院口腔科, |
| 基金项目： | “九五”军队科研基金资助项目课题 ( 98M 0 5 7) |
| 摘 要： | 目的：建立持续性高加速度（ Gz）重复作用下颞下颌关节变化的动物模型。方法：将雄性Wistar大鼠随机分成3组，对照组、 1Cz组和 10Gz组，每组12只。应用六九型动物离心机，离心加速度曲线为梯形， 10Gz峰值持续时间为30s，G值增长率约为0.5G/s，间隔 1Gz60s，连续每天5次，每周4d，共3周。结果：在实验中大鼠能逐渐适应固定和持续性高加速度（ Gz）重复作用，同时，成功地复制出颞下颌关节疾病的病理表现。结论：本动物模型重复性好，是研究正加速度对颞下颌关节影响比较理想的动物模型。 |
| 关 键 词： | 颞下颌关节 加速度 动物模型 病理 |
An animal model for the study on effects of repeated +Gz forces on temporomandibular joint |
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| YIN Yin,TIAN Hui ying,HU Min,MA Liang,YAO Jun,SUN Zheng yu,HOU Jun,LI Chuan bing. An animal model for the study on effects of repeated +Gz forces on temporomandibular joint[J]. Academic Journal of Pla Postgraduate Medical School, 2001, 22(4): 265-267 | |
| Authors: | YIN Yin TIAN Hui ying HU Min MA Liang YAO Jun SUN Zheng yu HOU Jun LI Chuan bing |
| Abstract: | Objective:To analysis the effects of repeated +Gz forces on the temporomandibular joint(TMJ), an animal model was established. Methods: 36 male Wistar rats were randomly divided into 3 groups, control group, +1Gz group, and +10Gz group. The control group was only fixed with rat-kept devices for 5 minutes. The +1Gz group was borne +1Gz for 5 minutes. The +10Gz group was repeatedly exposed +10Gz(each for 30s, onset rate about 0.5G/s, 5 times/d with +1Gz 1 minute intervals, 4d/wk, 3 Weeks in total. Results: The behaviors of these rats were described in details and pathologic injuries in TMJ were produced. Conclusion: The animal model, which has good repeatition and induces pathologic changes in different degrees under various experimental variables, is a perfect model to observe the effects of repeated +Gz stresses on TMJ. |
| Keywords: | Temporomandibular joint acceleration rats |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |