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Insights into the structure of class B GPCRs
Authors:Kaspar Hollenstein  Chris de Graaf  Andrea Bortolato  Ming-Wei Wang  Fiona H. Marshall  Raymond C. Stevens
Affiliation:1 Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, AL7 3AX, UK;2 Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands;3 The National Center for Drug Screening and the CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), 189 Guo Shou Jing Road, Shanghai, 201203, China;4 Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Abstract:
Keywords:class B G protein-coupled receptor (GPCR)   glucagon receptor (GCGR)   corticotropin-releasing factor receptor 1 (CRF1)   crystal structure   ligand binding
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