肺癌并发肺栓塞20例治疗体会

目的 总结临床肺癌患者并发肺栓塞的治疗经验体会.方法 收集20例肺癌并发肺栓塞患者的临床资料,包括患者的性别、年龄、侧别、肺癌病理性质及治疗预后等.结果 20例肺癌并发肺栓塞患者的年龄为(64.3±7.8)岁;男12例,女8例;病理活检显示,腺癌11例,鳞癌5例,小细胞肺癌4例;Ⅰ期2例,Ⅱ期3例,Ⅲ期7例,Ⅳ期8例.3例患者发生肺栓塞后24 h内死亡,8例患者发生肺栓塞后4周内死亡,其中最长生存时间为11.5个月.结论 肺癌并发肺栓塞的病死率较高,因此临床中应注意静脉血栓栓塞症风险评估,做好预防措施,确诊肺栓塞后应及时给予抗凝、溶栓、对症支持等治疗.

Treatment of lung cancer complicated with pulmonary embolism:a report of 20 cases

Objective To summarize the experience of treatment of pulmonary embolism in patients with lung can-cer. Method The clinical data of 20 patients with lung cancer complicated with pulmonary embolism were collected and analyzed, including patients'gender, age, lesion side, pathological properties of lung cancer, prognosis, etc. Result The 20 patients aged (64.3±7.8) years old, with 12 males and 8 females. Pathological biopsy results showed that there were 11 cases of adenocarcinoma, 5 cases of squamous cell carcinoma and 4 cases of small cell lung cancer;with regard to clini-cal stages, there were 2 cases of stage Ⅰ, 3 cases of stage Ⅱ, 7 cases of stage Ⅲ and 8 cases of stageⅣ. Three patients died in less than 24 hours from onset of pulmonary embolism, 8 patients died within four weeks, and the longest survival time was 11.5 months. Conclusion Lung cancer patients with pulmonary embolism have a relatively high mortality rate, so clinical attention should be paid to the risk assessment of venous thromboembolism, preventive measures should be taken, and timely treatment (such as anticoagulation, thrombolysis, symptomatic, etc.) should to be given upon the diagnosis of pulmonary embolism.