| 中药口腔生物黏附制剂的研究进展 |
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| 引用本文： | 段晓颖,闫艳仓,平佳宜,吴彩丽,陈天朝,刘雅敏. 中药口腔生物黏附制剂的研究进展[J]. 中国药事, 2011, 25(5): 503-506 |
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| 作者姓名： | 段晓颖 闫艳仓 平佳宜 吴彩丽 陈天朝 刘雅敏 |
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| 作者单位： | 1. 河南中医学院第一附属医院,郑州,450000
2. 河南中医学院 |
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| 摘 要： | 目的对近年来中药口腔生物黏附制剂的研究概况作一综述。方法根据国内外文献资料进行整理归纳。结果中药口腔生物黏附制剂是一种新型的药物释放系统,是以生物黏附材料为药物载体,通过生物黏附作用,长时间黏附于黏膜而发挥疗效,从而延长制剂在口腔中的滞留时间,控制药物的释放速度和释药量,使制剂产生最佳疗效。结论中药口腔生物黏附制剂对于治疗口腔局部病变方面有重要意义。
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| 关 键 词： | 中药口腔生物黏附制剂 生物黏附材料 黏附机制 |
Progress on Oral Mucosal Adhesive Preparations of TCM |
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| Duan Xiaoying,Yan Yancang,Ping Jiayi,Wu Caili,Chen Tianchao,Liu Yamin. Progress on Oral Mucosal Adhesive Preparations of TCM[J]. Chinese Pharmaceutical Affairs, 2011, 25(5): 503-506 |
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| Authors: | Duan Xiaoying Yan Yancang Ping Jiayi Wu Caili Chen Tianchao Liu Yamin |
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| Affiliation: | Duan Xiaoying,Yan Yancang1,Ping Jiayi1,Wu Caili1,Chen Tianchao and Liu Yamin1(The First Affiliated Hospital of Henan University of TCM,Zhengzhou,450000,1Henan University of TCM) |
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| Abstract: | Objective To introduce research progress on oral mucosal adhesive preparations of TCM in recent years.Methods Summarize literatures both in domestic and foreign.Results As a novel drug delivery system,oral mucosal adhesive preparations of TCM are based on bioadhesive materials for drug carriers,which can prolong the residence time of preparations in oral cavity as well as improve the intimacy with oral mucosal,and control the release rate and the amount of drug released from preparations by the bioadhesive ... |
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| Keywords: | oral mucosal adhesive preparations of TCM bioadhesive materials mechanism of adhesion |
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