新生儿窒息后cTnI的变化及其临床意义

目的 探讨血清心肌钙蛋白I（cTnI）在新生儿窒息后缺氧缺血性心肌损伤的诊断价值。方法 采用放射发光免疫法测定窒息新生儿组40例及对照组24例血清cTnI水平。结果 窒息新生儿组血清cTnI水平显著高于对照组（P〈0．01），且cTnI水平与窒息程度成正相关。结论 血清cTnI能较好反映新生儿窒息心肌损害程度。

The Changes and Clinical Significance of Cardiac Troponin I in Asphyxia Neonatorum

Objective To evaluate the diagnostic value of cardiac troponin I(cTnI)in determining myocardial damages in asphyxial newborn infants.Methods The serumal levels of cTnI were measured by radioimmunoassay in 40 cases with neonatal asphyxia and 24 normal infants served as control group.Results The levels of serumal cTnI in asphyxial neonates were significant higher than that in control group(P<0.01),and positively correlated to the degree of asphyxia.Conclusions The level of serumal cTnI could reflect the degree of myocardial damage, have great diagnostic value in asphyxia neonatorum.