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异氟醚控制性降压对颅内动脉瘤夹闭术病人血液动力学及组织氧合的影响
引用本文:王均炉!325000,林捷!325000,林海!325000,汪炜健!325000,陈必成!325000. 异氟醚控制性降压对颅内动脉瘤夹闭术病人血液动力学及组织氧合的影响[J]. 中华麻醉学杂志, 1999, 19(3): 0
作者姓名:王均炉!325000  林捷!325000  林海!325000  汪炜健!325000  陈必成!325000
作者单位:浙江省温州医学院附属第一医院麻醉科(王均炉!325000,林海!325000,汪炜健!325000),浙江省温州医学院附属第一医院心内科(林捷!325000),浙江省温州医学院附属第一医院外科实验室(陈必成!325000)
摘    要:


关 键 词:异氟烷  降压  控制性  氧耗    动脉瘤
修稿时间:1998-06-21

The effects of isoflurane-induced hypotension on oxygen delivery,oxygen consumption and oxygenation during cerebral aneurysm operation
Abstract:
Objective To study effect of isoflurane induced hypotension on hemodynamics and oxygen delivery (DO 2),oxygen consumption (VO 2),VO/DO 2 ratio (ERO 2) and oxygenation during cerebral aneurysm operation.Methods Twenty one cerebral anuerysm patients were operated on under general anesthesia Inhalation concentration of isoflurane was elevated to reduce MAP by 30% 40% during dissection and occlusion of the aneurysm ,and was maintained for 30 45min. Hemodynamic values were measurd with Swan Ganz technique. Hemodynamics,oxygen kinetics and the blood level of lactate were tested during isoflurane deliberated hypotension. Results No significiant changes of CO,CI,SV,SI,RVSWI,HR and ECG tracing were observed during hypotension (P<0 05) SVR,PVR,Cpp,RPP and LVSWI were significantly decreased during hypotension,(P<0 05) During controlled hypotension DO 2 and S v O 2 decreased significiantly, ERO 2 increased significiantly and VO 2 and plasma lactate concentraion remained unchanged.Conclusion Isoflurane induced hyppension can keep a good balance between DO 2 and VO2, during cerdbral aneurysm operation
Keywords:Isoflurane Hypotension  controlled Oxygen consumption Brain Aneurysm
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