不同材料双J管对兔输尿管的影响

目的：观察不同材料双J管对兔输尿管的影响。方法：本实验通过三种双J管置于15例（每一种双J管5例）正常兔的输尿管内，6周后观察其对输尿管上皮的损伤，输尿管的反应变化，双J管长壳的程度，置管前后肾盂压力的变化，结果：三种双J管均产生上皮细胞的损伤，二种国产双J管所引起的输尿管反应性较小。而进口双J管较重，与之相反，国产双J管长结古石的程度远较进口双J管严重（P＜0．05），置管6周后与管前比较肾盂压力无明显变化（P＜0．05），结论：国产双J管有较严重的长结石的倾向，但输尿管的反应性变化较小，适合于短时间置管，进口双J管的输尿管反应性变化较重，便有较长长结石倾向，比较适合于篚置管，尽管这些为动物实验所得结果，但也可能与临床有关系。

The Effect of Various Double-J Materials on the Normal Rabbit Ureter

Objective:To observe the effect of various double-J materials on the normal rabbit ureter.Methods:3 different types of double J were used totaling 15 ureter units.Intra-pelvic pressure values were measured before and after 6 week of intubation,the ureter were observed by scaning electron microscopy and histological analysis.Results:The superfical epithelial destruction was severe in three double J types.Inflammatory reactive changes were milder in the ureter intubated with PUR and silicon-isiertes PVC stents than the hydrogel-coated stent.The intra-pelvic pressure were not change after 6 weeks of intubation.Conclusions:The study demonstrated the hydrogel-coated stent to be more suitable than PUR and silicon-isiertes PVC sents.being less prone to encrustation.A knowledge of the potential effects of these is essential to minimize complication related to use.