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| Growth process of small pancreatic carcinoma： A case report with imaging observation for 22 months | |
| 作者姓名： | Hisa T Ohkubo H Shiozawa S Ishigame H Takamatsu M Furutake M Nobukawa B Suda K |
| 作者单位： | Takeshi Hisa（Department of Internal Medicine, Saku Central Hospital, Nagano 384-0301,Japan） ; Hiroki Ohkubo（Department of Surgery, Saku Central Hospital,Nagano 384-0301, Japan） ; Satoshi Shiozawa（Department of Clinical Pathology, Saku Central Hospital, Nagano 384-0301, Japan） ; Hiroki Ishigame（Department of Clinical Pathology, Saku Central Hospital, Nagano 384-0301, Japan） ; Masato Takamatsu（Department of Internal Medicine, Saku Central Hospital, Nagano 384-0301, Japan） ; Masayuki Furutake（Department of Internal Medicine, Saku Central Hospital, Nagano 384-0301, Japan） ; Bunsei Nobukawa（Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan） ; Koichi Suda（Department of Pathology, Tokyo-West Tokusyukai Hospital, Tokyo, Japan） ; |
| 摘 要： | This report describes serial observations of the growth process of a small invasive ductal carcinoma （IDC） of the pancreas from imaging studies. Histopathological studies showed IDC with macroscopic retention cysts proximal to an intraductal papillary-mucinous adenoma with mild atypia of the branch duct type in the pancreatic body, with no relation between the two lesions. IDC was demonstrated as an extremely low-echoic mass resembling a cyst with an unclear margin on the initial endoscopic ultrasonography. We misinterpreted the lowechoic mass as a benign intraductal mucinous-papillary neoplasm （IPMN） based on findings of other imaging studies, and the patient was followed-up. The mass increased from 7 mm to 13 mm in diameter over 22 mo, and remained smaller than 10 mm in diameter for about 420 d. The tumor volume doubling time was 252 d. The Ki67 labeling index was 15.9%, similar to that described in previous reports. Hence, IDC may grow slowly while remaining small. |
| 关 键 词： | 胰腺癌 入侵癌细胞 肿瘤 生长过程 |
| 收稿时间： | 2007 Sep 20 |
Growth process of small pancreatic carcinoma: a case report with imaging observation for 22 months |
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| Hisa T,Ohkubo H,Shiozawa S,Ishigame H,Takamatsu M,Furutake M,Nobukawa B,Suda K.Growth process of small pancreatic carcinoma: a case report with imaging observation for 22 months[J].World Journal of Gastroenterology,2008,14(12):1958-1960. | |
| Authors: | Hisa Takeshi Ohkubo Hiroki Shiozawa Satoshi Ishigame Hiroki Takamatsu Masato Furutake Masayuki Nobukawa Bunsei Suda Koichi |
| Institution: | 1. Department of Internal Medicine, Saku Central Hospital, Nagano 384-0301,Japan 2. Department of Surgery, Saku Central Hospital,Nagano 384-0301, Japan 3. Department of Clinical Pathology, Saku Central Hospital, Nagano 384-0301, Japan 4. Department of Internal Medicine, Saku Central Hospital, Nagano 384-0301, Japan 5. Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan 6. Department of Pathology, Tokyo-West Tokusyukai Hospital, Tokyo, Japan |
| Abstract: | This report describes serial observations of the growth process of a small invasive ductal carcinoma (IDC) of the pancreas from imaging studies. Histopathological studies showed IDC with macroscopic retention cysts proximal to an intraductal papillary-mucinous adenoma with mild atypia of the branch duct type in the pancreatic body, with no relation between the two lesions. IDC was demonstrated as an extremely low-echoic mass resembling a cyst with an unclear margin on the initial endoscopic ultrasonography. We misinterpreted the low-echoic mass as a benign intraductal mucinous-papillary neoplasm (IPMN) based on findings of other imaging studies, and the patient was followed-up. The mass increased from 7 mm to 13 mm in diameter over 22 mo, and remained smaller than 10 mm in diameter for about 420 d. The tumor volume doubling time was 252 d. The Ki67 labeling index was 15.9%, similar to that described in previous reports. Hence, IDC may grow slowly while remaining small. |
| Keywords: | Invasive ductal carcinoma Pancreas Intraductal papillary-mucinous neoplasm Endoscopic ultrasonography Tumor volume doubling time |
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