小剂量Isovist脑室造影CT扫描诊断脑室系统非肿瘤性疾病的实验与临床研究

用乳胶囊制成脑积水和脑室囊虫病的模型,行Isovist造影CT扫描.结果:造影剂浓度(V/V)0.5%～1%时CT值65.1～128.3Hu,造影效果良好.浓度过小,对比度不足.效果不佳.浓度过高,将有较多伪影,可淹没或掩盖病变.以0.5%～1%Isovist脑室造影CT扫描44例,43例得到明确诊断,造影效果良好.其中交通性脑积水2例,室间孔粘连1例,导水管狭窄2例,正中孔粘连5例,脑室囊虫病33例,经手术和病理证实诊断符合率为100%.1例注人造影剂后距扫描时间过短,造影剂尚未扩散到病变部位而失败.

Experiment and clinical study of small dose Isovist CT-ventriculo- graphy for diagnosis of nontumor disease in the ventricular system

A model of hydrocephalus and ventricular cysticercosis were made by emulsion cyst and detected by Isovist CT-ventriculography scanning. Results; When concentration of contrast medium was 0. 5%-l%,the CT number was 65. 1-128. 3 Hu,the effect of CT-ventriculography was the best. When concentration was higher,it produced false image and the focus was covered. 44 patients had undergone Isovist CT-ventriculography , 43 cases gain definite diagnosis. Of them,2 cases with communicating hydrocephalus , 1 case with foramen Monro adhesion, 2 cases with aqueduct stenosis, 5 cases with foramen Magendie adhesion, 33 cases with cysticercosis. The rate of correct diagnosis was 100%, which was confirmed by operation and pathology. One patient had a fail CT-ventriculography, because the interval time was too short for the contrast medium had not diffused thoroughly to the location of the lesion.