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河南省驻马店市HIV单阳家庭随访特征分析
引用本文:王璐,金霞,葛增,单多,高省,周建平,何文生,汪宁.河南省驻马店市HIV单阳家庭随访特征分析[J].疾病控制杂志,2011(1):39-41.
作者姓名:王璐  金霞  葛增  单多  高省  周建平  何文生  汪宁
作者单位:中国疾病预防控制中心性病艾滋病预防控制中心;北京协和医学院;驻马店市疾病预防控制中心;
摘    要:目的了解河南省驻马店市HIV单阳家庭的基本特征及随访管理情况。方法收集HIV单阳家庭阳性者的基本信息、医疗行为、性行为特征、及CD4+ T淋巴细胞变化情况,并采集阴性配偶的血样检测HIV血清阳转情况。结果本次调查共随访3 724户HIV单阳家庭,阴性配偶中有3 718人进行HIV检测,13人出现HIV阳转。最近1次性生活安全套使用率为98.9%。治疗病例组CD4+ T淋巴细胞计数呈明显上升趋势;换药组CD4+ T淋巴细胞计数变化较为稳定;未治疗组CD4+T淋巴细胞计数变化未见统计学差异。结论驻马店市HIV单阳家庭阴性配偶的血清HIV抗体阳转率较低。接受抗病毒治疗后效果明显,CD4+ T淋巴细胞计数明显上升,而未治疗的HIV感染者和病人的CD4细胞计数变化规律还需进一步开展研究,以期为选择抗病毒治疗时机和修改抗病毒治疗策略提供参考。

关 键 词:获得性免疫缺陷综合征  HIV  CD4淋巴细胞计数  

Characteristics analysis of HIV single-infection couples in Zhumadian City,Henan Province
WANG Lu,JIN Xia,GE Zeng,SHAN Duo,GAO Xing,ZHOU Jian-ping,HE Wen-sheng,WANG Ning..National Center for AIDS/STD Control , Prevention,Chinese Center for Disease Control , Prevention,Beijing ,China,.Peking Union Medical College,Beijing ,.Zhumadian Center for Disease Control , Prevention,Zhumadian.Characteristics analysis of HIV single-infection couples in Zhumadian City,Henan Province[J].Chinese Journal of Disease Control and Prevention,2011(1):39-41.
Authors:WANG Lu  JIN Xia  GE Zeng  SHAN Duo  GAO Xing  ZHOU Jian-ping  HE Wen-sheng  WANG NingNational Center for AIDS/STD Control  Prevention  Chinese Center for Disease Control  Prevention  Beijing  China  Peking Union Medical College  Beijing  Zhumadian Center for Disease Control  Prevention  Zhumadian
Institution:WANG Lu1,JIN Xia1,GE Zeng1,2,SHAN Duo1,GAO Xing1,ZHOU Jian-ping3,HE Wen-sheng3,WANG Ning1.1.National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 100050,China,2.Peking Union Medical College,Beijing 100730,3.Zhumadian Center for Disease Control and Prevention,Zhumadian 463000
Abstract:Objective To understand the characteristics and follow-up management of HIV single-infection couples in Zhumadian,Henan Province.Methods Information on medical,sexual behaviors and CD4 count changes were collected,and blood specimens of the HIV-negative partners were collected for testing HIV.Results A total of 3 724 HIV single-infection couples were followed up in Zhumadian and 3 718 negative partners were tested for HIV infection in which 13 people showed HIV sero-positive conversion.The rate of condom us...
Keywords:Acquired immunodeficiency syndrome  HIV  CD4 lymphocyte count  
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