Extended venous thromboembolism prophylaxis for high-risk patients undergoing surgery for malignancy

Background

In surgical patients with known malignancy, the odds ratio for an episode of a venous thromboembolism is approximately 6.5 compared to a group of patients without malignancy undergoing the same procedure [Heit et al.: Arch Intern Med 2000;160:809–815].

Case Report

We present a case of a 46-year-old Caucasian male with a history of adenocarcinoma of the rectum. The patient received neoadjuvant treatment prior to low anterior resection with diverting colostomy. He received short-term prophylaxis for venous thrombosis, but unfortunately developed a blood clot in a lower extremity several weeks after surgery.

Conclusion

There is a well-defined role in carefully selected patients for the use of extended prophylaxis to prevent venous thromboembolic complications following cancer surgery.Key Words: Venous thromboembolism prophylaxis, Venous thromboembolism, Surgery, Deep vein thrombosis, Pulmonary embolism