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Practical guidelines for treating inflammatory bowel disease safely with anti‐tumour necrosis factor therapy in Australia
Authors:W. Connell  J. M. Andrews  S. Brown  M. Sparrow
Affiliation:1. St Vincent's Hospital, Melbourne, Victoria,;2. Royal Adelaide Hospital and University of Adelaide, Adelaide, South Australia,;3. Department of Gastroenterology, Royal Adelaide Hospital, Adelaide and;4. The Alfred and Box Hill Hospitals, Melbourne, Victoria, Australia
Abstract:Anti‐tumour necrosis factor (TNF) therapy is an effective but expensive option for treating inflammatory bowel disease (IBD). Its use is generally reserved for patients with severe refractory disease, often involving long‐term administration. Anti‐TNF therapy has the potential to be associated with various adverse effects, such as infection, malignancy and immunogenicity. Clinicians and patients should be familiar with these possibilities and adopt appropriate precautions prior to and during treatment to minimize risk. Guidelines have been developed for Australian prescribers intending to use anti‐TNF therapy in IBD by a Working Party commissioned by IBD‐Australia, a Special Interest Group affiliated with the Gastroenterology Society of Australia.
Keywords:Crohn's disease  anti TNF therapy  adalimumab  infliximab  ulcerative colitis  guidelines.
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