A 3-month comparison of 1% and 2% carteolol and 0.5% timolol in open-angle glaucoma |
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| Authors: | William C. Steward M. Bruce Shields Robert C. Allen Richard A. Lewis John S. Cohen H. Dunbar Hoskins John N. Hetherington Robert L. Bahr Jean E. Noblin John T. Delehanty |
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| Affiliation: | (1) Department of Ophthalmology, University of South Carolina, Charleston, SC, USA;(2) Duke Eye Center, Duke University, Box 3802, 27710 Durham, NC, USA;(3) Department of Ophthalmology, University of Virginia Medical Center, Charlottesville, Va, USA;(4) Sacramento, California, USA;(5) Cincinnati Eye Institute, Cincinnati, Ohio, USA;(6) San Francisco, California, USA;(7) Providence, Rhode Island, USA;(8) Burroughs Wellcome Co. Research, Triangle Park, NC, USA |
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| Abstract: | ![]()
Carteolol, a nonselective beta-adrenergic antagonist with intrinsic sympathomimetic activity, was compared in 1% and 2% topical solutions with 0.5% timolol in 105 patients with primary open-angle glaucoma. In this double-masked, randomized 3-month trial, all three preparations significantly lowered intraocular pressure throughout the study, with no significant differences being observed. There were also no significant differences among the three preparations with regard to ocular or systemic adverse reactions, including heart rate and blood pressure.Offprint requests to: M.B. Shields |
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