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Amebic liver abscess in a european patient: Zymodeme classification ofentamoeba histolytica
Authors:Th. Weinke  B. Friedrich-Jänicke  P. G. Sargeaunt  M. Trautmann  K. Janitschke
Affiliation:(1) Robert Koch-Institut, Fachgebiet Klinische Parasitologie, Berlin;(2) Landesinstitut für Tropenmedizin, Berlin;(3) Department of Medical Protozoology, London School of Hygiene and Tropical Medicine, London;(4) Klinikum Charlottenburg der FU Berlin, Abteilung für Innere Medizin mit Schwerpunkt Infektionskrankheiten, Berlin
Abstract:Summary This is a case report of a 36-year-old patient who developed an amebic liver abscess after a stay in the Sudan. He was first misdiagnosed as having pneumonia of the right lower lobe. Following establishment of the correct diagnosis, the patient recovered fully after metronidazole treatment. The fecal culture in Robinson's medium yielded extensive growth ofEntamoeba histolytica. Electrophoretic characterization proved it to be a zymodeme XIX, which is one of the zymodemes associated with pathogenicity in the host. This first report of a zymodeme classification ofE. histolytica in Germany should initiate further epidemiological studies.Abkürzungsverzeichnis E. histolytica Entamoeba histolytica - GPI glucose phosphate isomerase - ME malic enzyme - PGM phosphoglucomutase - HK hexokinase - MIFC Merthiolate-iodine-formaldehyde concentration technique
Keywords:Entamoeba histolytica  Amebic liver abscess  Zymodeme  Isoenzymes  Electrophoresis
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